Epidemiology

Etiology

Pathophysiology

Clinical features

Immunocompetent patients

• > 90%: asymptomatic course
• < 10%: CMV mononucleosis
  • Fever, malaise, myalgia/arthralgia, fatigue, headache
  • Less common: sore throat, cervical lymphadenopathy, hepatomegaly, splenomegaly
  • Differential diagnosis: infectious mononucleosis caused by EBV

Diagnostics

Treatment

• Preferred: ganciclovir or valganciclovir
• Alternatives: foscarnet, cidofovir